0737. Statins protect the vasculature from excessive angpt-2 production in sepsis
نویسندگان
چکیده
Introduction Sepsis is a syndrome of systemic inflammation arising from infection that constitutes a top-ten cause of adult mortality. The recent withdrawal of a specific sepsis therapeutic has diminished pharmaceutical enthusiasm for developing novel drugs in this domain. Angiopoietin-2 (Angpt-2) is an endothelial-derived protein that potentiates vascular inflammation and permeability and may be involved in sepsis pathogenesis.
منابع مشابه
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